Malignant ecrine poroma or porocarcinorna is a tumor originating from the acrosiringeal cells. It is very rare and tends to metastasize on the skin (epidermostropism), in the limph nodes and the viscerae. We report a case of a 56 year old caucasian woman with a malignant ecrine poroma localized on the pahn of her left palm. It was treated with surgery and radiotherapy in a period of 14 years, each time resulting in an incomplete recovery. The tumor recurred. To eliminate the ulcered lesion on the readiodermatitis a treatment with radiofrequency and cryosurgery was recommended. This treatment resulted in the healing of the skin and conservation of the total function of the hand.